KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CENPE
All Species:
9.39
Human Site:
S1566
Identified Species:
17.22
UniProt:
Q02224
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q02224
NP_001804.2
2701
316415
S1566
A
K
D
S
A
L
Q
S
I
E
S
K
M
L
E
Chimpanzee
Pan troglodytes
XP_001170168
2701
316707
S1566
V
K
H
S
A
L
Q
S
I
E
S
K
M
L
E
Rhesus Macaque
Macaca mulatta
XP_001110512
2701
316828
S1566
A
K
D
S
T
L
Q
S
I
E
S
K
M
L
E
Dog
Lupus familis
XP_852631
1216
141588
V228
N
C
D
G
S
V
K
V
S
H
L
N
L
V
D
Cat
Felis silvestris
Mouse
Mus musculus
Q6RT24
2474
286506
E1484
T
Q
L
E
E
S
Q
E
E
M
K
T
L
R
E
Rat
Rattus norvegicus
Q7TSP2
1385
159522
G397
Q
L
S
Q
F
T
S
G
Q
L
T
P
G
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_420670
2150
248600
R1162
E
M
S
T
M
T
E
R
D
D
D
D
F
K
M
Frog
Xenopus laevis
NP_001080954
2954
339950
R1747
E
L
E
Q
S
Q
H
R
L
Q
C
E
I
E
E
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524993
2013
231091
E1025
S
Q
L
E
Q
E
I
E
E
K
S
A
L
M
E
Honey Bee
Apis mellifera
XP_001121311
1418
164919
S430
L
P
T
I
K
E
I
S
E
I
P
N
R
K
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781622
2537
290578
K1495
E
E
E
G
R
V
V
K
Q
D
S
Q
L
S
D
Poplar Tree
Populus trichocarpa
XP_002308893
1247
142380
G259
N
K
S
L
M
T
L
G
T
V
I
K
K
L
S
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_187629
1348
152938
S360
L
R
S
K
L
K
T
S
H
S
D
H
S
E
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
95.7
37.8
N.A.
60.5
21.2
N.A.
N.A.
37.1
31
N.A.
N.A.
26.1
24.8
N.A.
25.5
Protein Similarity:
100
99.2
98
42
N.A.
75
35.7
N.A.
N.A.
55
52.2
N.A.
N.A.
45.6
37.8
N.A.
48.8
P-Site Identity:
100
86.6
93.3
6.6
N.A.
13.3
0
N.A.
N.A.
0
6.6
N.A.
N.A.
13.3
6.6
N.A.
6.6
P-Site Similarity:
100
86.6
93.3
46.6
N.A.
26.6
6.6
N.A.
N.A.
20
46.6
N.A.
N.A.
46.6
6.6
N.A.
53.3
Percent
Protein Identity:
23.9
N.A.
N.A.
24.9
N.A.
N.A.
Protein Similarity:
34.6
N.A.
N.A.
37.6
N.A.
N.A.
P-Site Identity:
20
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
20
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
0
0
0
16
0
0
0
0
0
0
8
0
0
0
% A
% Cys:
0
8
0
0
0
0
0
0
0
0
8
0
0
0
0
% C
% Asp:
0
0
24
0
0
0
0
0
8
16
16
8
0
0
16
% D
% Glu:
24
8
16
16
8
16
8
16
24
24
0
8
0
16
54
% E
% Phe:
0
0
0
0
8
0
0
0
0
0
0
0
8
0
0
% F
% Gly:
0
0
0
16
0
0
0
16
0
0
0
0
8
0
0
% G
% His:
0
0
8
0
0
0
8
0
8
8
0
8
0
0
0
% H
% Ile:
0
0
0
8
0
0
16
0
24
8
8
0
8
0
0
% I
% Lys:
0
31
0
8
8
8
8
8
0
8
8
31
8
16
0
% K
% Leu:
16
16
16
8
8
24
8
0
8
8
8
0
31
31
0
% L
% Met:
0
8
0
0
16
0
0
0
0
8
0
0
24
8
8
% M
% Asn:
16
0
0
0
0
0
0
0
0
0
0
16
0
0
0
% N
% Pro:
0
8
0
0
0
0
0
0
0
0
8
8
0
0
0
% P
% Gln:
8
16
0
16
8
8
31
0
16
8
0
8
0
0
0
% Q
% Arg:
0
8
0
0
8
0
0
16
0
0
0
0
8
8
0
% R
% Ser:
8
0
31
24
16
8
8
39
8
8
39
0
8
16
24
% S
% Thr:
8
0
8
8
8
24
8
0
8
0
8
8
0
0
0
% T
% Val:
8
0
0
0
0
16
8
8
0
8
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _